The film centres on the relationship between Oliver (played by Kutcher) and Emily (played by Peet), who first met on a flight from Los Angeles to New York seven years ago, only to decide that they were poorly suited together.

Over the next seven years they keep meeting each other, becoming acquaintances and then close friends; going through different partners and careers at the same time.

With each of them suffering through one failed relationship after another, they finally figure out after seven years that they might be right for each other after all. Courtesy of http://en.wikipedia.org/wiki/ A_Lot_Like_Love.